Carl W. Gottschalk Research Scholar Grant Recipients
2024
Jeffrey A. Beamish, MD, PhD
Control of proximal tubule metabolism by Pax8 in ischemic kidney injury
Andrew Samuel Beenken, MD, PhD
"Structural mechanisms of ligand binding by cubilin in the proximal
tubule
Scott M. Krummey, MD, PhD
Role of CD43 Signaling on Effector CD8+ T Cells in Acute Rejection
Kyle McCracken, MD, PhD
FOXI1-dependent genetic mechanisms of human intercalated cell development
Jennifer A. Schaub, MD
A systems biology approach to identify cortical and medullary gene regulatory networks related to Hypoxia Inducible Factor-1A
Nicholas J. Steers, PhD
Elucidating the role of T-follicular like helper cells promoting the activation of B-cells in IgA Nephropathy
2023
Cary R. Boyd-Shiwarski, MD, PhD
The role of calcineurin inhibitors on blood pressure and potassium homeostasis through WNK body molecular condensates
Georgina Gyarmati, MD, PhD, MPH
Role of the newly discovered neuroendothelial cells in renal physiology and disease
Matthew Bruce Lanktree, MD, PhD, FASN
Multi-omics in PEXIVAS: using precision medicine to improve risk stratification in ANCA Vasculitis
Yoshiharu Muto, MD, PhD
Role of methionine cycle in remodeling of epigenetic landscape in acute kidney injury and failed repair
Insa Marie Schmidt, MD, MPH
A deep learning framework for the automated assessment of kidney pathology and prognosis
Anand Srivastava, MD, MPH
Functional MRI for Enhanced Phenotyping of CKD
2022
Leo Francis Buckley, PharmD, MPH
Pharmacoproteomic Investigation of Colchicine Pharmacology in Chronic Kidney Disease
Florian Buerger, MD, PhD
Delineating the role of secreted semaphorin 3G in monogenic and acquired glomerulopathies and studying its potential protective effect for the kidney's glomerular filtration barrier.
Eman Y. Gohar, MS, PhD
Intrarenal Estrogen Biosynthesis as a Novel Regulator of Renal Sodium Handling
Vivek Kasinath, MD
Targeted Nanotherapeutics for Renal Cell Carcinoma
Kenneth Lim, MD, PhD, FASN
Translating biological discoveries in Klotho into a therapeutic strategy for CKD-associated cardiac fibrosis.
Sandhya S. Thomas, MD, FASN
SIRP? Mediates Insulin/IGF1 Receptor Signaling in CKD-Induced Cardiomyopathy
Clintoria R. Williams, PhD
Renoprotective Properties of Zinc Supplementation in Chronic Kidney Disease
2021
Eirini Kefalogianni, PhD
Immunomodulatory roles of circulating TNFR1/2 in diabetic nephropathy
Ronak Lakhia, MD
Role of Cis-Regulatory Elements in Autosomal Dominant Polycystic Kidney Disease
Eugene Lin, MD, MS, FASN
The Impact of Medicare Advantage on Patients with End-Stage Kidney Disease
Jennie Lin, MD, MS, FASN
Endoplasmic Reticulum Stress and Macrophage Function in APOL1 Nephropathy
Alla Mitrofanova, PhD
STING as a potential therapeutic target for diabetic kidney disease
Evan C. Ray, MD, PhD, FASN
Regulation of Divalent Cation Homeostasis by Muc1
Yanhua Wang, PhD
Roles of aldosterone and phosphatases in vasopressin escape
2020
Mark R. Hanudel, MD, MS, FASN
The Pathologic Effects of Fibroblast Growth Factor 23 Fragments
Sho Morioka, MSc, PhD
Boosting apoptotic cell removal during acute kidney injury
Sanjeev Noel, PhD
T cell TIGIT/CD226 co-signaling in acute kidney injury and repair
Jin Wei, PhD
Role of macula densa RXFP1 in gestational hypertension
Ting Yang, MD, PhD
Renal epithelial actions of the prostaglandin EP4 receptor in blood pressure control
Jie Zhang, PhD
A new mechanism for the sex differences in diabetic glomerular hyperfiltration and kidney injury
2019
Subhashini Bolisetty, PhD
Targeting ferritin in sepsis-associated acute kidney injury
Louise Christine Evans, PhD
Pathological role of T-cells in salt-sensitive hypertension
Naoka Murakami, MD, PhD, FASN
Roles of immune checkpoint signaling in autoimmune kidney diseases
Sagar U. Nigwekar, MD
Novel Determinants of Calcific Uremic Arteriolopathy
Tengis S. Pavlov, PhD
Mechanism and role of ATP release in polycystic kidney diseases
Fahad Saeed, MD, FASN
Pilot Testing of a Communication Intervention to Promote Shared Renal Replacement Therapy Decision Making in Older Patients with Chronic Kidney Disease (RRT- SDM Trial)
Tomokazu Souma, MD, PhD
Harnessing Antioxidative Stress Pathways in Renal Epithelial Progenitors to Prevent AKI-to-CKD Transition
2018
Alexander Grabner, MD
The Role of FGF23 and FGFR4 in Cardio-renal Syndrome
Hana A. Itani, PhD, FASN, MBA
New Immune Mechanisms in Hypertension
David E. Leaf, MD, MS, MSc, FASN
Hepcidin, Dysregulated Iron Homeostasis, and Anemia in Human Acute Kidney Injury
Ali Poyan-Mehr, MD
Metabolic And Molecular Predictors of Acute Kidney Injury in Humans and Their Clinical Response to NAD+ Augmentation
Roderick J. Tan, MD, PhD
Tubular-to-Glomerular Crosstalk in Proteinuric Chronic Kidney Disease
Brandi M. Wynne, PhD
Renal Dendritic Cell-Derived Interleukin 6 Increases Sodium Reabsorption and Blood Pressure
2017
Amandeep Bajwa, PhD
Mitochondria Transfers to Prevent Ischemic Reperfusion Injury in Transplant
Wei Chen, MD, MS, FASN
Calcification Propensity, using Dynamic Light Scattering, to Study Vascular Calcification in Patients with Advanced Chronic Kidney Disease
Paul G. DeCaen, PhD
Defining ADPKD-2 Mutation Effects on Ciliary PKD2 Ion Channels
Kevin F. Erickson, MD, MS, FASN
Dialysis Facility Closures and their Effect on Costs, Health Outcomes, and Access to Care
Nicholas J. Ferrell, PhD
Extracellular matrix-mediated mechanotransduction in diabetic nephropathy
Aaron J. Polichnowski, PhD
Deleterious Effects of TNF-α on the AKI-CKD Nexus
2016
Jennifer R. Charlton, MD, MS
Detecting renal pathology in mouse model of prematurity using MRI-based biomarkers
Benjamin S. Freedman, PhD
Modeling Human Kidney Disease with Pluripotent Stem Cells
Sarah C. Huen, MD, PhD
The Role of Kidney FGF21 in Surviving Sepsis
Sang-Ho Kwon, MS, PhD
Exosome biogenesis in renal tubule growth and acute kidney injury
Joshua M. Stern, MD
Evidence for a Distinct Gut Microbiome in Kidney stone patients
Crystal A. West, PhD
Proteinase-activated receptor 2 (PAR2) in the altered renal electrolyte handling of pregnancy
2015
Mitsi A. Blount, PhD
Compartmentalized Regulation of Urea Permeability in the Inner Medullary Collecting Duct
Paul E. Drawz, MD, MS
Treatment of Masked Hypertension
Nadja Grobe, PhD
Molecular Imaging of the Renin Angiotensin System for the Discovery of Novel Biomarkers in Chronic Kidney Disease
Mark Parker, PhD
Cause and Consequence of Acidosis by the Sodium/bicarbonate Cotransporter NBCe1
Nirupama Ramkumar, MD, MPH, FASN
Functional Role of Nephron Prorenin Receptor in Regulation of Blood Pressure, Sodium and Water Homeostasis
Matt G. Sampson, MD
Genetic Risk in Nephrotic Syndrome from an Integrative Genomics Approach
Jennifer M. Sasser, PhD
Mechanisms and Mediators of the Preeclamptic Phenotype in the Dahl S Rat
2014
Michael Butterworth, PhD
Aldosterone-Regulated MicroRNAs and Sodium Transport in the Distal Kidney Nephron
Kirk N. Campbell, MD, FASN
Role of Dendrin in Glomerular Disease Progression
Krzysztof Kiryluk, MD
GWAS-based Pathogenesis Model of IgA Nephropathy
Timmy C. Lee, MD, MPH, FASN
Natural History of Arteriovenous Fistula Maturation
Ethan P. Marin, MD, PhD
A Novel Mode of Vascular Function Regulation by Protein Palmitoylation
Brian B. Ratliff, PhD
Posttranslational and Redox Modification Regulation of HMGB1 During Kidney Injury
Matthias Tilmann Wolf, MD, PhD, FASN
The Role of Mucin 1 in Protection Against Nephrolithiasis by Regulation of the Renal Calcium Channel TRPV5
2013
Matthew K. Abramowitz, MD, MS, FASN
Metabolic Acidosis and Insulin Resistance in Chronic Kidney Disease
Michelle L. Gumz, PhD
Role of the Kidney in Blood Pressure Regulation by the Circadian Protein Per1
Tamara Isakova, MD, MMSc
Longitudinal Assessments of Sclerostin in Chronic Kidney Disease
Pinelopi P. Kapitsinou, MD
Role of Endothelial Oxygen Sensing in Kidney Injury and Repair
Mara McAdams-DeMarco, PhD
Frailty and Adverse Health Outcomes of Aging in Older Adults with Kidney Failure
Jennifer L. Pluznick, PhD
Elucidating the Function of Renal Olfactory Receptor 1393
Aylin R. Rodan, MD, PhD, FASN
Mechanisms of NKCC Regulation in the Drosophila Renal Tubule
2012
Christian Faul, PhD
The Role of Fibroblast Growth Factor 23 in Cardiorenal Syndrome
Puneet Garg, MD, FASN
Shp2 a Non-receptor Tyrosine Phosphatase Regulates Nephrin Phosphorylation and Podocyte Mobility
Michal L. Melamed, MD
Vitamin D and Cardiovascular Risk Factors in Kidney Disease
Farzana Perwad, MD
Role of FGF-23 in Cardiovascular Complications in Chronic Kidney Disease
Rosemary V. Sampogna, MD, PhD
Circadian Clock Genes as Determinants of Kidney Architecture, Nephron Number and Hypertension
Weibin Zhou, PhD
Zebrafish Model of Steroid-Sensitive Nephrotic Syndrome
2011
Kerri L. Cavanaugh, MD, FASN
Targeting Social Determinants to Improve Chronic Kidney Disease Care
Anna Greka, MD, PhD
Regulation of Podocyte Actin Dynamics by Angiotensin/TRPC Channel Signaling
Hatim A. Hassan, MD, PhD, FASN
Leptin Signaling and Oxalate Hemostasis: Relevance to Calcium Oxalate Kidney Stone Disease
Oleh Pochynyuk, PhD
Purinergic Control of Mechano-Sensitivity in the Distal Nephron
Bernd Schroppel, MD
Immune Regulatory Mechanisms of Autophagy During Transplantation Tolerance
Pamela Vivian Tran, PhD
Molecular Mechanism of THM1-Mediated Renal Cystogenesis
Shao-Ling Zhang, PhD
Role of Reactive Oxygen Species (ROS) in Maternal Diabetes-Induced Perinatal Programming
2010
Vivek Bhalla, MD, FASN
Molecular Mechanisms of Salt-Sensitive Hypertension in Insulin Resistance
David M. Charytan, MD, MS, MSc
Microvascular Density in the Hearts of Individuals with and without CKD: Invasive and Non-Invasive Studies
Paolo Fiorina, MD
B7.1 on Podocytes: A New Therapuetic Target for Diabetic Nephropathy
Akio Kobayashi, PhD
Genetic Regulation of Nephron Progenitor Cells
Vladimir Pech, MD
The Role of HCO3- in ENaC Regulation
Timo Rieg, MD, PhD
Role of Big Conductance K Channels in K Secretion
Simone Sanna-Cherchi, MD
Search for Rare Structural Variants in Kidney and Urinary Tract Malformations
2009
Francesca Di Sole, PhD
Adenosine A1 Receptor Activation Regulates Salt and Fluid Homeostasis: A Novel Adaptive Mechanism in Acute Ischemia/Reperfusion Injury
William Henry Fissell, MD
Could the GBM be the Filtration Barrier? Pressure, Permeability, and the ECM
Benjamin D. Humphreys, MD, PhD, FASN
The Role of Indian Hedgehog in Recovery from Acute Kidney Injury
Sung Il Kim, PhD
Role of TGF-Beta-Activated Kinase 1 (TAK1) in TGF-Beta-Induced ECM Remodeling and Renal Cell Death
X. Sean Li, MD
Formation And Maintenance of Renal Epithelial Cells
Hua Ann Jenny Lu, MD, PhD, FASN
Novel Function of AQP2 on Kidney Tubulogenesis
Uptal D. Patel, MD
Impact of Automated Reporting of Kidney Function in the Veterans Affairs Healthcare System
Ganesan Ramesh, PhD
Regulation of Inflammation By Netrin-1 In Ischemia Reperfusion Injury Of The Kidney
Johannes S. Schlondorff, MD, PhD
Mechanisms of TRPC6-Mediated Podocytopathy
Shuxia Wang, MD, PhD
Protective Role of PKG in Renal Ischemia-Reperfusion Injury
Daniel E. Weiner, MD, MS, FASN
Medical, Economic and Ecologic Implications of Dialyzer Reprocessing
Jing Yu, PhD
Molecular Regulation of Mammalian Renal Medulla Formation
2008
Brian D. Adair, PhD
Structure Analysis in PKD2 Membrane Channels
Markus Bitzer, MD
TGF-b and MicroRNAs in Renal Disease
Ion Alexandru Bobulescu, MD
Reulgation of the Renal Sodium/Proton Exchanger NHE3 by Dopamine: Role of Protein Phosphatase 2A
Tarek M. El-Achkar, MD, FASN
A Novel Protective Role for Tamm-Horsfall Protein in Kidney Injury
Sarah Faubel, MD
The Role of IL-6 in Lung Injury after Acute Kidney Injury
Michal Mrug, MD
Role of Complement Component 3 in Polycystic Kidney Disease Pathogenesis
Samir M. Parikh, MD, FASN
PGC1-alpha in Septic Acute Kidney Injury
Alexander Staruschenko, PhD, FASN
Regulation of ENaC by Small G Proteins and Cytoskelton
Farook Thameem, PhD
Susceptibility Gene Search for GFR in Diabetes
2007
Shuta Ishibe, MD
Role of Met Receptor in Kidney Development and Repair
Anil K. Karihaloo, PhD
Role of VEGF During Early Embroyonic Kidney Development
Susan M. Kiefer, PhD
Kidney and Ureter Abnormalities of Pax2/Sall4 Compound Mice
S. Todd Lamitina, PhD
Regulation of Osmotic Stress Responses by the MAP Kinase Gene Lit-1 in C. Elegans
Reena Rao, PhD
Contribution of Renal Collecting Duct Sodium Transport to the Metabolic Syndrome
Ikuyo Yamaguchi, MD, PhD
Regulation of the Renal Microvasculature by Placental Growth Factor and Vascular Endothelial Cadherin During Chronic Kidney Disease
Wenzheng Zhang, PhD
Generation and Characterizations of CNT/CD-Specific Dot1a-Deficient Mice as a Novel Liddle's Syndrome Model
2006
Patrick Cunningham, MD, FASN
Mechanisms of Injury in Endotoxin Induced Acute Renal Failure
Jeremy Stuart Duffield, MD, MBChB, PhD
Macrophage Delivered Wnt Signaling in the Development of Progressive Fibrosis in the Kidney
Kenneth R. Hallows, MD, PhD, FASN
Mechanisms of Epithelial Na Channel Regulation by AMP-Activated Protein Kinase
Fangming Lin, MD, PhD, FASN
Isolation and Characterization of Murine Renal Stem/Progenitor Cells
Zubaida R. Saifudeen, PhD
Role of p53 in Early Kidney Development
Michael Zeisberg, MD
The Role of integrinI in Epithelial-Mesenchymal Transition in Renal Fibrosis
2005
Thomas J. Carroll, PhD
Stephen I-Hong Hsu, MD, PhD
Timothy A. Sutton, MD, PhD, FASN
2004
Robyn A. Cunard, MD
Neil A. Hukriede, PhD
Snezana Petrovic, MD, MEd, PhD, FASN
2003
Dorin-Bogdan Borza, PhD
Yumay Chen, PhD
Christine Maric-Bilkan, PhD, FASN
2002
Patrick D. Brophy, MD
Sumant S. Chugh, MD, FASN
S. Ananth Karumanchi, MD
Janos Peti-Peterdi, MD, PhD
2001
Carlton M. Bates, MD
Zheng Dong, PhD, FASN
James D. Stockand, PhD, FASN
2000
John M. Arthur, MD, PhD, FASN
Rulan S. Parekh, MD, MS, FASN
1999
Jeffrey C. Fink, MD, MS, FASN
Susan E. Quaggin, MD, FASN
1998
Raghu Kalluri, MD, PhD, FASN
Alan S.L. Yu, MBChB
1997
Bradley K. Yoder, PhD
1996
Jonathan M. Barasch, MD, PhD